Abstract

Emerging global evidence points to country of origin as an important risk factor for developing gastric cancer (GC). Immigrants from high-incidence countries for GC may retain an increased risk despite living in low-incidence regions, and precursor lesions such as intestinal metaplasia may be more common in foreign-born individuals than in individuals born in the United States, particularly within high-risk racial/ethnic groups.1,2 Although the United States had 51 million immigrants in 2020—the highest number of foreign-born residents globally—data on the association between immigrant status and GC risk within the United States remain limited.

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