Abstract

As the most common cancer in humans, basal cell carcinomas (BCCs) affect approximately 2.8 million people. Depending on the location, size, tumor subtype, and other factors, treatment may include topical therapy with imiquimod or 5-fluorouracil, cryotherapy, radiation, photodynamic therapy, electrodesiccation and curettage, surgical excision, and Mohs micrographic surgery, the latter of which has the lowest 5-year recurrence rate: between 0.7% and 2.4%. BCC is mainly a localized neoplasm, although less commonly, it can become locally advanced or even metastatic (0.0028–0.55%). Locally advanced BCC (laBCC) and metastatic BCC (mBCC) are both considered advanced BCC

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