Heavy Metals Content in Whole Blood (Literature Review and Case Study)

Olena Bezkrovna,Irina Skorokhod,Lesya Zakrutko

doi:10.53933/sspmpm.v2i1.41

Abstract

Heavy metals content in whole blood was analyzed for Kyiv city residents, who were tested in 2019-2020 years. According to obtained results, the metals were divided into three group. 1) with elevated concentration in statistical sample and elevated threshold (mercury and arsenic); 2) with elevated concentrations for several patients while average concentration for sample did not exceed threshold (lead); 3) with single cases of increased concentrations that are not a risk to the health of the population, but pose a threat to a particular patient (Bi, Cd, Cr, Mo, Cs, Va). Some metals never exceeded the maximum allowable concentrations Al, Ba, Be, Au, Co, Cu, Mn, Ni, Pd, Pt, Sr, Ti, U, Zr). We recommend regular check-up for the concentrations of mercury and arsenic in blood, because these metals are the factors of population risk. When the metals concentrations in blood are elevated, the diagnosis should be established taking into account clinical history of the patient.

Highlights

Nowadays, an increasing environmental and global public health concern, related with environmental contamination by heavy metals, are well known
Serum concentrations of Zn, Ni and Al in women with endometrial polyps indicated that the serum median levels of were found to be statistically lower in the study group when compared with the control group [5]
We divided the detected levels of heavy metals in whole blood into three groups according to obtained data (Table 1)

Summary

Introduction

An increasing environmental and global public health concern, related with environmental contamination by heavy metals, are well known. For male reproductive system it has been proven that four heavy metals (As, Zn, Mn, Sb) were significantly and positively associated with prostate cancer risk [1] and cause spermiation defects [2]. It was shown, that Ni, Cu, and Zn may play a role in the pathogenesis of polycystic ovary syndrome related to reproductive hormone [3]. The Cu/Zn ratio, as a biomarker of oxidative stress, was statistically higher in the study group with endometrial polyps It suggests the role of oxidative stress in etiopathogenesis of this disease [5]

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