Heavy metal analysis, pesticide residue analysis and aflatoxin assay of siddha herbal formulationmadhumega nivarani chooranam

Abstract

Aim
 The aim of the study was to assess the Heavy metal analysis, pesticide residue and aflatoxin assay of Siddha herbal formulation “Madhumega Nivarani Chooranam”, used for the management of Madhumegam (Type-II Diabetes mellitus)
 Materials and Method
 According to the procedure that is stated in the Siddha text "The Pharmacopoeia of Siddha Research Medicines," the siddha poly herbal formulation was formulated in accordance with good manufacturing practises (GMP) regulations. Aflatoxin assay, pesticide residue analysis, and heavy metal analysis these studies were all carried out at Nobel Research Solutions in Chennai.
 Results
 The above assay, which used AAS to identify Heavy metals in the siddha medicine Madhumega Nivaran iChooranam revealed BDL (below detective level), presence of lead and arsenic at 1.14 PPM and 0.34 PPM level as listed in the table. The study revealed absence of Aflatoxin and pesticide residues in the given sample. It is indicating that this drug is safe to use.
 Conclusion
 According to the results, the sample Madhumega Nivarani Chooranam (MNC) has been determined to be safe throughout the present screening process, with the presence of heavy metals below the detection limit, Devoid of aflatoxins, as well as Residues of Pesticides. Hence, the current study reveals the drug was safe for therapeutic use