Heating loss mechanism in β-NaFeO2 nanoparticles for cancer treatment under alternating field

Abstract

The induction heating loss mechanism in nanofluids prepared using synthesized β-NaFeO2 nanoparticles has been discussed concerning optimization of magnetic relaxation (Neel and Brownian) losses, specific absorption rate (SAR), intrinsic loss power (ILP)as well as the concentration of nanoparticles. The highest value of SAR for β-NaFeO2 nanoparticles is 705.86 W/g at 335.2 Oe field and 267 kHz frequency. The value of Brownian and total relaxation time has been calculated theoretically and found to be τB= 6.126 × 10−4 sand τ = 2.668 × 10−7 s, respectively. For Hyperthermia treatment, 2 to 5 mg/mL is the best suitable lowest concentration to achieve high SAR and ILP under applied field. The maximum value of ILP observed is 1.49 nHm2/kg. The calculated theoretical and experimental parameters of induction heating make synthesized β-NaFeO2 nanoparticles suitable for the treatment of cancer via Hyperthermia.