Heartlogic Heart Failure Index As Covid Index: Predicting Severity Of Covid-19 In Patients With Advanced Heart Failure

Abstract

Heart Logic heart failure diagnostic is a personalized, remote heart failure diagnostic and monitoring system using multiple, novel physiologic sensors. It has been proven to have high sensitivity and low-alert burden that combines sensor data into one composite index that provides weeks of advance notice for detecting early signs of worsening heart failure. We present two cases, one with non-ischemic cardiomyopathy, the other with ischemic cardiomyopathy. In both cases, patients had reduced ejection fraction status post cardiac resynchronization therapy defibrillator who were monitored with Heart Logic heart failure diagnostics. In the first case, a rapid increase in sensors alarmed us for impending exacerbation of heart failure and retrospective analysis of differentials led us to diagnosis of COVID-19. The patient developed increase in respiratory rate, mean heart rate and S3 component of heart sound while decrease in thoracic impedance, ultimately with increased Index. Patient was admitted, intubated and successfully recovered. Heart Logic Index helped us making the diagnosis in early stage of COVID-19 and manage effectively. We present another case of ischemic cardiomyopathy with reduced ejection fraction awaiting heart transplant due to severe multi vessel coronary artery disease who tested positive for COVID-19 with milder symptoms. He was monitored prospectively to assess changes in Heart Failure Index which remained normal correlating with the milder symptoms from COVID-19 itself. All the indices including S1, S3, respiratory rate and mean heart rate remained normal. Patient recovered without any major residual effects from COVID 19. Hence, heartlogic index could serve as proactive alert tool like a “COVID index” to suspect, correlate with severity of symptoms and monitor the outcome in patients of heart failure diagnosed with COVID-19.