Abstract

To propose a new method for real-time monitoring of blood pressure of blood loss (BPBL), this article combines pulse transit time (PTT) and heart rate variability (HRV) as input parameters to build a model for BPBL estimation. In this article, effective parameters such as PTT, R-R interval (RRI), and HRV were extracted and used to establish the blood pressure (BP) estimation. Three BP estimation models were created: the PTT model, the RRI model, and the HRV model, and they were divided into an experimental group and a control group. Finally, the effects of the different estimation models on the accuracy of BPBL were evaluated using the experimental results. The result showed that both the RRI model and the HRV model have a good improvement effect on the prediction accuracy of BPBL, and the HRV model has the highest prediction accuracy than the PTT model and the RRI model. The correlation coefficients between the actual systolic BP (SBP) and diastolic BP (DBP) and the estimated SBP and DBP of the HRV model were 0.9580 and 0.9749, respectively, and the root-mean-square error of the HRV model for both SBP and DBP were 7.59 and 6.56mmHg, respectively. The results suggest that the accuracy of the BPBL estimated by the HRV models is better than that of the PTT model, which means that HRV seems to be more effective in improving the accuracy of BP estimation compared with RRI. These results in this article provide a new idea for other researchers in the field of BPBL estimation research.

Highlights

  • Introduction to the experimental processDuring the experiment, bloodletting and blood transfusion were performed when the physiological state of the pig was stable, and the speci c number of times was determined by the physiological state of the pig

  • The results suggest that the accuracy of the blood pressure under blood loss (BPBL) estimated by the R-R internal (RRI) and heart rate variability (HRV) models is better than that of the pulse transit time (PTT) model, which means that both RRI and HRV can enhance the accuracy of BPBL estimation, and HRV seems to be more effective in improving the accuracy of blood pressure (BP) prediction compared to RRI

  • Three different BPBL estimation models were tested with the same experimental data, and the experimental results of the training set and the estimation set of systolic BP (SBP) under blood loss were obtained

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Summary

Introduction

Introduction to the experimental processDuring the experiment, bloodletting and blood transfusion were performed when the physiological state of the pig was stable, and the speci c number of times was determined by the physiological state of the pig. ECG, and PTT is calculated by ECG and PPG These characteristic parameters are used to estimate the BPBL model. To propose a new method for real-time monitoring of human blood pressure under blood loss (BPBL), this article combines pulse transit time (PTT) and heart rate variability (HRV) as input parameters in order to establish a model for the estimation of BPBL. The blood pressure (BP) of the human body changes rapidly during blood loss which cannot be monitored dynamically [8], it will greatly affect the timely judgment of the condition and the effect of any treatment provided. It is important to establish a non-invasive, fast, simple, and effective method of BP estimation to monitor its change under blood loss. This study combines HRV and the existing pulse transit time (PTT) theory to establish a novel BP estimation model, which is able to provide continuous and efficient

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