Abstract

Aim. To study the morpho-functional parameters of the heart in convalescents of hemorrhagic fever with renal syndrome (HFRS) using echocardiography.Material and methods. The study included 27 patients without any chronic diseases who had severe or moderate HFRS (the main group) within 3 weeks after their discharge from the infection diseases hospital. The reference group consisted of 19 patients comparable by age and gender, without any chronic diseases. Transthoracic echocardiography was the basic method of heart and hemodynamics investigation. The test was performed using tissue Doppler and non-Doppler assessment of left ventricle systolic deformation method (speckle-tracking method).Results. Violation of longitudinal systolic deformation of the left ventricle was observed in 15 (55.6%) patients, which was combined with diastolic left ventricle filling by the type of relaxation violation in 8 (29.6%) cases. Mitral valve insufficiency of 1 degree was identified in 11 (40.7%) HFRS patients, insufficiency of the tricuspid valve of 1 degree was identified in 4 (14.8%) patients. Pericardial effusion was detected in 2 (7.4%) patients. In 7 (25.9%) patients in the first 3 weeks after discharge from the hospital, additional floating echoes were detected on the leaves and fibrous ring of the aortic valve, which were considered as a manifestation of thromboendocarditis.Conclusion. Further investigation is necessary to assess the prognostic value (including the risk of thromboembolic complication developing) of the changes revealed in HFRS convalescents and to support the inclusion of echocardiography in the examination program during dispensary observation of HFRS-convalescents.

Highlights

  • Transthoracic echocardiography was the basic method of heart and hemodynamics investigation

  • In 7 (25.9%) patients in the first 3 weeks after discharge from the hospital, additional floating echoes were detected on the leaves and fibrous ring of the aortic valve, which were considered as a manifestation of thromboendocarditis

  • Further investigation is necessary to assess the prognostic value of the changes revealed in hemorrhagic fever with renal syndrome (HFRS) convalescents and to support the inclusion of echocardiography in the examination program during dispensary observation of HFRS-convalescents

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Summary

Material and methods

The study included 27 patients without any chronic diseases who had severe or moderate HFRS (the main group) within 3 weeks after their discharge from the infection diseases hospital. In 7 (25.9%) patients in the first 3 weeks after discharge from the hospital, additional floating echoes were detected on the leaves and fibrous ring of the aortic valve, which were considered as a manifestation of thromboendocarditis. Изменения сердечно-сосудистой системы при геморрагической лихорадке с почечным синдромом (ГЛПС) вносят весомый вклад в клиническую картину заболевания. Наиболее доступной визуализирующей методикой оценки состояния сердца при ГЛПС является эхокардиография (ЭХОКГ) [1,2,5]. В контексте значимости сердечно-сосудистых изменений при ГЛПС особого внимания заслуживают данные, свидетельствующие о высоком риске коронарных и мозговых сосудистых катастроф после перенесенного заболевания [7]. Цель работы: изучить морфофункциональные параметры сердца у реконвалесцентов ГЛПС с использованием ЭХОКГ

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