Hearing the Vagus Nerve’s Rhythm in Patients with Paroxysmal Atrial Fibrillation

Abstract

Purpose of the study : to evaluate hearing the vagus nerve’s rhythm in patients with paroxysmal atrial fibrillation. Materials and methods . Observations were carried out in 50 patients with paroxysmal atrial fibrillation who were admitted for catheter-based treatment of arrhythmia. Cardiorespiratory synchronism test was carried out not in atrial fibrillation attack during sinus rhythm with the help of VNS-Micro instrument and software determining the regulatory adaptive status of the human body. The early depolarization zone in the right atrium was mapped using circulatory navigation 20-pole LASSO NAV. Carto-3 system was used to build an electro-anatomic isochronous model of sinus rhythm of the right atrium. The automatic method of annotation of CONFIDENCE module points was applied. At least 500 activation points in the right atrium were set. The observational data and computed values, subject to normal distribution, were processed by parametric statistic techniques using STATISTICA 10.0 software. Results. It has been established that in subjects with low regulatory adaptive capabilities, the length of atrial fibrillation anamnesis amounted to 5.8±0.7 years, and in case of good and satisfactory capabilities — 2.9±0.5 years. The Pearson correlation coefficient between the area of early depolarization zone in the right atrium and disease duration was equal to 0.92. Conclusion. The length of atrial fibrillation correlates with the regulatory adaptive status and area of the early depolarization zone in the right atrium.