Abstract
Introduction: Patients with chronic kidney diseasesuffer from sensorineural hearing loss as a complication.The prevalence, type and degree of hearing loss along with the associated factors like age, electrolyte imbalance, hypertension, diabetes, duration and stage of CKD were studied.
 Methodology:This was a prospective cross-sectional study conducted in the department of Otorhinolaryngology and Nephrology at Nobel Medical College & Teaching Hospital, Kanchanbari, Biratnagar, Nepal from1st August 2018 to 30th September 2019.After thorough history taking, clinical & biochemical examinations, all patients underwent Tuning fork test and Pure tone audiometry. CKD was staged according to the eGFR. Data were stored in excel spreadsheet and analysis was done using the SPSS software (version 21)
 Result: Out of 150 patients,the ratio of male to female was 1.2:1. The mean age of the patients was 44.04 ± 10.524 years. 68 (45%) patients had CKD stage V with a median duration of 24 (18 – 36) months. The prevalence of hearing loss was found to be 83 (55.3%), most of them in bilateral ear (58%). The staging of CKD had a significant association with the prevalence of hearing loss and its severity. The duration of the illness had a strong association with hearing loss.
 Conclusion: This study shows that sensorineural hearing loss prevails in the patients suffering from CKD, which increases with age, duration of CKD, presence of comorbidities like hypertension, diabetes and level of serum urea and creatinine. However, it could not establish diabetes and electrolyte as a potential risk factor for developing hearing loss from CKD.
Highlights
God created human beings with nine holes on their body surface popularly referred in some old religious literature as “Naba-daar” which are essen al for survival
This study shows that sensorineural hearing loss prevails in the pa ents suffering from Chronic Kidney Disease (CKD), which increases with age, dura on of CKD, presence of comorbidi es like hypertension, diabetes and level of serum urea and crea nine
Contrary to the common belief the incidence and prevalence of hearing loss, both subclinical and overt is high in pa ents with Chronic Kidney Disease (CKD)
Summary
God created human beings with nine holes on their body surface popularly referred in some old religious literature as “Naba-daar” (nine doors) which are essen al for survival. There are mul ple shared risk factors for CKD and hearing loss including age, diabetes, hypertension and medica ons that are both ototoxic and nephrotoxic, electrolyte disturbance, uremic toxin, metabolic disturbances and haemodialysis. All these established facts permit to infer that the link between inner ear damage and kidney failure is likely to be much more than a coincidental finding.[3] So, pa ents with CKD suffer widespread complica ons and sensorineural hearing loss is one of them
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