Abstract
This chapter describes the Healthy Ageing across the Life Course (HALCyon) NDA collaborative research project, the aim of which was to investigate biological and social factors from early life that influence healthy ageing in later life. Healthy ageing was studied as optimal functioning at the individual level, in terms of physical and cognitive capability and wellbeing. The roles of lifetime socioeconomic circumstances, cognitive development and education, body size and diet were investigated, as well as underlying biology (the hypothalamic-pituitary-adrenal (HPA) axis, telomeres and genes). The project undertook: systematic reviews and meta-analyses of all available studies; comparative analysis using harmomised data across nine British cohort studies; in depth analysis of single cohorts with unique data; and qualitative interviews with sub-samples of participants from three of these cohorts.
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