Abstract

BackgroundAlthough older diabetes patients with unique characteristics should be cared carefully to improve their health-related quality of life (HRQOL), the association between diabetes and HRQOL remain unclear, especially in Asians. We aimed to compare the HRQOL between older Chinese patients with type 2 diabetes (T2D) and their age-gender-matched controls.MethodsOlder patients with T2D were recruited from a community hospital in Suzhou located in the east part of China while controls were selected from a community-based health survey of older adults aged 60 years or older. HRQOL of cases and controls was assessed by the EQ-5D-3L. The impact of T2D on HRQOL was investigated using a liner regression model and the relationship between T2D and EQ-5D health problems was evaluated using logistic regression models.ResultsA total of 220 cases and 440 controls were included. The mean age of the participants was 68.8 years and women accounted for 69.1% of the study sample. The EQ-5D-3L index score was lower for older people with T2D (0.886) than their controls (0.955). After multivariable adjustment, the difference in ED-5D-3L index score between older people with and without T2D was 0.072. In logistic regression analyses, T2D was positively associated with reporting of problems in mobility (odds ratio [OR] = 5.00); pain/discomfort (OR = 1.66), and anxiety/depression (OR = 3.2).ConclusionsT2D has a detrimental effect on HRQOL of older Chinese people.

Highlights

  • Diabetes has become one of the most common chronic diseases among older Chinese people (i.e. 60 years or older), with the prevalence being 20.4% [1] and more than 22.5% [2] in two major studies

  • The EQ-5D-3L index score was lower for older people with type 2 diabetes (T2D) (0.886) than their controls (0.955)

  • T2D was positively associated with reporting of problems in mobility; pain/discomfort (OR = 1.66), and anxiety/depression (OR = 3.2)

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Summary

Introduction

Diabetes has become one of the most common chronic diseases among older Chinese people (i.e. 60 years or older), with the prevalence being 20.4% [1] and more than 22.5% [2] in two major studies. It is estimated that more than 50% of patients with diabetes in China are above 60 years [3]. Given the robust increase in life expectancy and dramatic increase in the prevalence of unhealthy diet and lifestyle due to rapid economy growth and social development, the number of older peoples with diabetes will continue to increase in China. Older patients with diabetes have several unique characteristics as older people are more vulnerable and susceptible to diseases. Diabetes associates with an excess mortality risk [4] as well as a shorter life expectancy among older adults[5]. Qazvin University of Medical Sciences, ISLAMIC REPUBLIC OF IRAN

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