Abstract
BackgroundTo compare changes in health-related quality of life (HRQoL) in young (18–25 years) versus older (≥ 26 years) adults up to 5 years after Roux-en-Y gastric bypass (RYGB).MethodsData on Short Form-36 (SF-36) and obesity-related problems scale (OP) at baseline and 1, 2, and 5 years after RYGB were extracted from the Scandinavian Obesity Surgery Registry. Within-group changes and the effect of age group on 5-year changes in SF-36 and OP were analyzed. Effects sizes (ESs) were calculated.ResultsA total of 2542 young and 12,425 older adults were included at baseline, and 138 young (20.7% of those eligible) and 1021 older (31.8%) adults were followed-up 5 years post-RYGB. At this time, average to large improvements (ES ≥ 0.5) were observed in physical functioning, physical component score and OP in young adults, and in physical functioning, role physical, general health, physical component score, and OP in older adults (all, p ≤ 0.001). Both age groups displayed negligible to weak (ES < 0.5) or no improvements in mental HRQoL (all, p < 0.55). Older adults displayed greater 5-year improvements than their young counterparts in role physical, general health, vitality, social functioning, physical component score, and obesity-related problems scale (all, p < 0.05).ConclusionsBoth young and older adults displayed improvements in OP and physical HRQoL 5 years post-RYGB compared to baseline, while mental HRQoL did not improve to the same extent. Greater HRQoL-improvements could be expected in older patients why future research on HRQoL post-RYGB should stratify data on age groups.
Highlights
Obesity is associated with poor general and weight-related quality of life (HRQoL), most notably in pre-bariatric surgery populations as compared to non-bariatric surgery or non-treatment seekers [1,2,3,4], and health-related quality of life (HRQoL) is increasingly acknowledged as an important outcome after bariatric surgery besides weight loss and remission of co-morbidities [5]
While adults and adolescents display long-term improvements, physical dimensions, of HRQoL after bariatric surgery, including control group comparisons with and without obesity [3, 5,6,7,8], less is known about post-surgical HRQoL in young adults
For obesity-related problems scale, a positive coefficient denotes that the change was smaller in young versus older adults b Adjusted for health-related quality of life component at baseline, comorbidity, weight loss at 5 years, adverse events and surgical access added to the list of predictors according to the present results
Summary
Obesity (body mass index [BMI] ≥ 30 kg/m2) is associated with poor general and weight-related quality of life (HRQoL), most notably in pre-bariatric surgery populations as compared to non-bariatric surgery or non-treatment seekers [1,2,3,4], and HRQoL is increasingly acknowledged as an important outcome after bariatric surgery besides weight loss and remission of co-morbidities [5]. Results A total of 2542 young and 12,425 older adults were included at baseline, and 138 young (20.7% of those eligible) and 1021 older (31.8%) adults were followed-up 5 years post-RYGB At this time, average to large improvements (ES ≥ 0.5) were observed in physical functioning, physical component score and OP in young adults, and in physical functioning, role physical, general health, physical component score, and OP in older adults (all, p ≤ 0.001). Older adults displayed greater 5-year improvements than their young counterparts in role physical, general health, vitality, social functioning, physical component score, and obesity-related problems scale (all, p < 0.05). Conclusions Both young and older adults displayed improvements in OP and physical HRQoL 5 years post-RYGB compared to baseline, while mental HRQoL did not improve to the same extent. Greater HRQoL-improvements could be expected in older patients why future research on HRQoL post-RYGB should stratify data on age groups
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