Abstract

Background: The healthcare burden of persistent cough is rarely evaluated. This study aimed to characterize healthcare resource use and cost in people with chronic and acute cough. Methods: Data were from the UK Clinical Practice Research Datalink (CPRD) with linked hospital data. Adults were selected if they had a cough record in March 2014–February 2015 and were classified as having chronic or acute cough (Holden SE, et al. Curr Med Res Opin 2020;36:139–150). All healthcare contacts and prescriptions over the study year were costed at 2019 prices. Results: Of 150,231 patients, 12,513 (8.3%) had chronic cough (CC), 38,599 (25.7%) had acute cough with ≥2 cough events and 99,119 (66.0%) had acute cough with one event in the study year. For each healthcare type, the highest use frequencies and costs were observed in CC; the greatest disparities originated in primary care. Conclusions: Chronic cough was associated with substantially increased healthcare use and costs. Patients’ older age profile and possible comorbidity should be considered in interpreting the results.

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