Abstract

Background:The prevalence of multimorbidity in low- and middle-income countries (LMICs) is thought to be rising rapidly. Research on the state of healthcare for multimorbidity in LMICs is needed to provide an impetus for integration of care across conditions, a baseline to monitor progress, and information for targeting of interventions to those most in need. Focusing on multimorbid cardiometabolic disease in India, this study thus aimed to determine 1) the proportion of adults with co-morbid diabetes and hypertension who successfully completed each step of the chronic disease care continuum from diagnosis to control for both conditions, and 2) how having additional cardiovascular disease (CVD) risk factors is associated with health system performance along the care continuum for diabetes, hypertension, and co-morbid diabetes and hypertension.Methods:Using a nationally representative household survey carried out in 2015 and 2016 among women aged 15–49 years and men aged 15–54 years, we created a ‘cascade of care’ for diabetes, hypertension, and co-morbid diabetes and hypertension by determining the proportion of those with the condition who had been diagnosed, were on treatment, and achieved control. We used Poisson regression with a robust error structure to estimate how having additional cardiovascular disease (CVD) risk factors (diabetes, hypertension, current smoking, and obesity) was associated with reaching each cascade step for diabetes, hypertension, and co-morbid diabetes and hypertension.Findings:Seven hundred thirty-four thousand seven hundred ninety-four adults were included in the analysis. Among individuals with co-morbid diabetes and hypertension, 28·8% (95% CI, 26·7%–31·0%), 16·1% (95% CI, 14·4%–17·9%), and 3·7% (95% CI, 2·8%–4·9%) – with these proportions varying between states by a factor of 4·8, 7·9, and 56·8 – were aware, treated, and achieved control of both conditions, respectively. Men, adults with lower household wealth, and those living in rural areas were less likely to reach each cascade step. Having additional CVD risk factors generally did not increase the probability of reaching each cascade step for diabetes, hypertension, and co-morbid diabetes and hypertension, except that having concurrent diabetes increased the probability of successfully transitioning through the hypertension care cascade.Interpretation:While varying widely between states and population groups, health system performance for co-morbid diabetes and hypertension is generally low in India, and there appears to be little integration of care across CVD risk factors.Funding:European Research Council.

Highlights

  • Efforts to improve health in low- and middle-income countries (LMICs) have largely focused on single conditions (e.g., HIV or malaria) or technologies [1, 2]

  • Efforts to move towards health systems that can provide high-quality care across NCDs and tailor care to individuals’ comorbidities are crucial in resource-poor settings because 1) health systems in LMICs are often weak and fragmented [4], 2) strengthening primary care to improve management of NCDs will likely have benefits for infectious disease care, such as through a higher ability to deal with new epidemics, and 3) the time and, compared to local incomes, financial burden of accessing care tends to be higher in LMICs compared to high-income settings [6], meaning that many patients with multimorbidity can ill-afford to visit a specialty clinic for each of their conditions

  • This study aims to provide this evidence for cardiovascular disease (CVD) risk factors in India

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Summary

Introduction

Efforts to improve health in low- and middle-income countries (LMICs) have largely focused on single conditions (e.g., HIV or malaria) or technologies (e.g., vaccines) [1, 2]. Research has an important role to play in guiding this transition from health services that provide care for single diseases to systems that effectively care for the multi-morbid patient in LMICs. describing the state of healthcare for those with multiple chronic conditions can provide 1) an impetus for policy makers to move towards integration of care across diseases, 2) a baseline that allows for monitoring of progress over time, and 3) important information for the appropriate targeting of interventions to those most in need. Focusing on multimorbid cardiometabolic disease in India, this study aimed to determine 1) the proportion of adults with co-morbid diabetes and hypertension who successfully completed each step of the chronic disease care continuum from diagnosis to control for both conditions, and 2) how having additional cardiovascular disease (CVD) risk factors is associated with health system performance along the care continuum for diabetes, hypertension, and comorbid diabetes and hypertension

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