Abstract

Rational medicines use (RMU) is the prescribing/dispensing of good quality medicines to meet individual patient's clinical needs. Policy-makers, managers and frontline providers play critical roles in safeguarding medicine usage thus ensuring their rational use. This study investigated perspectives of key health system actors on prescribing practices and factors influencing these in Eswatini. Public sector healthcare service delivery is through health facilities (public sector, not-for-profit faith-based, industrial) and community-based care. A qualitative, exploratory study using semi-structured in-depth interviews with seven policymakers and managers, and 32 facility-based actors was conducted. Drawing on Social Practice Theory, material (health system context), competence (provider) and cultural (patient and provider) factors influencing prescribing practices were explored. Participants were aged between 21-57years, had been practicing for 1-30 years, and were a mix of doctors, nurses, pharmacists and pharmacy-technicians. Factors contributing to irrational medicines use included: poor use of treatment guidelines, lack of RMU policies, poorly-functioning pharmaceutical and therapeutics committees, stock-outs of medicines, lack of pharmacy personnel in primary healthcare facilities, and restrictions of medicines by level of care. Provider-related factors included: knowledge, experience and practice ethic, symptomatic prescribing, high patient numbers. Patient-related factors included late presentation, language, and the need to be prescribed many medicines. In Eswatini, prescribing practices are influenced by the interaction of factors (health system, provider and patient) that span levels (facility, region, and policy-making) of the health system. Promoting RMU thus goes beyond the availability of guidelines and provider training and requires concerted efforts of multiple stakeholders.

Highlights

  • Rational use of medicines is crucial to well-functioning health systems

  • This study investigated perspectives of key health system actors on prescribing practices and factors influencing these in Eswatini

  • Factors contributing to irrational medicines use included: poor use of treatment guidelines, lack of Rational medicines use (RMU) policies, poorly-functioning pharmaceutical and therapeutics committees, stock-outs of medicines, lack of pharmacy personnel in primary healthcare facilities, and restrictions of medicines by level of care

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Summary

Introduction

The World Health Organization (WHO) considers that medicines are used rationally when individual patients are prescribed and dispensed correct medicines, of good quality, in appropriate doses to meet their clinical needs, at a minimal cost to them and their community, and for an appropriate duration of treatment [1]. Frontline providers (prescribers and pharmacy personnel) ensure that medicines are ordered from the central medical stores (CMS), stored correctly, and used rationally. This research draws on the Social Practice Theory (SPT) to study prescribing practices in public sector and not-for-profit faith-based facilities in the Kingdom of Eswatini (formerly Swaziland, and hereafter referred to as Eswatini). Rational medicines use (RMU) is the prescribing/dispensing of good quality medicines to meet individual patient’s clinical needs. Policy-makers, managers and frontline providers play critical roles in safeguarding medicine usage ensuring their rational use. Public sector healthcare service delivery is through health facilities (public sector, not-for-profit faith-based, industrial) and community-based care

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