Health status of newborns from mothers with severe uncontrolled bronchial asthma

Abstract

The main aim of research to study the health status of newborns born to mothers with severe asthma (BA) who received systemic GKS during pregnancy. The clinical and functional status of 65 patients with severe steroid-dependent asthma in the dynamics of pregnancy and the health status of their newborns (group I) were studied. Comparison group - 60 children from mothers without chronic respiratory diseases (group II Most of the patients had no control over BA symptoms during pregnancy - 51 (78.5%), worsening of the disease during pregnancy was noted. In one case, antenatal fetal death at 22 weeks of gestation was noted in a patient against the background of severe exacerbation of asthma. In mothers who received systemic GC, newborns had lower weight and height indicators, their average body weight was 3078 ± 110 g, whereas in the comparison group - 36352 ± 112 g (p<0.05), length - 48.0 ± 0.7 cm, in group II - 53.5 ± 0.9 cm (p<0.05). A greater number of pathological conditions were noted, among which prematurity was more often observed - in 25 (38.5%) in group I and 7 (11.7%) in group II (p <0.05), caesarean section - in 44 (69.2 %) in group I, while in group II - 16 (26.7%), a more serious condition at birth, resuscitation measures were carried out by 30 (46.1%) newborns in group I. In group I the predominance prevailed: intrauterine infection - in 43 (66.2%), in group II - in 21 (35%), intrauterine fetal growth retardation - in 21 (32.3%) and 7 (11.7%), respectively. Children from mothers with severe uncontrolled asthma were distinguished by a high frequency of disharmonious development, multiple organ damage to the systems, which dictates the need for preventive measures in pregnancy.