Abstract
BackgroundIn the past few decades, Lebanon has witnessed a significant increase in the incidence rates of women diagnosed with breast cancer. This increase, which is associated with the advancements in treatment modalities, emphasizes the need to evaluate the health-related quality of life (HRQoL) of women with breast cancer and to compare its patterns before and after breast-conserving surgery (BCS).ObjectiveThis study aims to describe changes in HRQoL according to body image pre- and post-BCS and just before initiation of adjuvant therapy in newly diagnosed patients with breast cancer in Lebanon.MethodsA prospective cohort study targeting Lebanese women newly diagnosed with breast cancer and who have an indication for BCS will be conducted in 2 health care facilities. Baseline characteristics and clinical data will be collected. The European Organization for Research and Treatment of Cancer Quality-of-Life cancer-specific and breast cancer–specific questionnaires will be used to assess HRQoL. The outcomes will be measured at baseline and 1 day after breast surgery. The primary outcome will be the body image dimensions of the Quality-of-Life breast cancer–specific questionnaire. Statistical analyses will include descriptive statistics, paired 2-tailed t test, and stepwise multiple regression. A total of 120 patients will be required.ResultsA total of 120 patients were enrolled in the study. Future outcomes will be published in professional peer-reviewed health-related research journals.ConclusionsThis study is strengthened by its follow-up nature, allowing us to draw conclusions about causality. The results of this study will identify the most affected components of HRQoL, as well as the factors that could play a role in improving HRQoL among women undergoing BCS. The findings of this study will help decision makers, physicians, and social workers to design a comprehensive program with multidisciplinary components for the management and care of patients with breast cancer in Lebanon.International Registered Report Identifier (IRRID)DERR1-10.2196/27893
Highlights
BackgroundApproximately 2.1 million women were newly diagnosed with breast cancer in 2018 worldwide [1]
A significant number of Lebanese women are diagnosed with an incidence rate that has been on the rise over the years, going from a reported 1451 cases in 2005 to 3219 cases in 2018 [8,9,10]
This study aims to describe changes in the health-related quality of life (HRQoL) according to body image pre- and post-breast-conserving surgery (BCS) and just before initiation of adjuvant therapy in newly diagnosed patients with breast cancer in Lebanon
Summary
BackgroundApproximately 2.1 million women were newly diagnosed with breast cancer in 2018 worldwide [1]. In the past few decades, Lebanon has witnessed a significant increase in the incidence rates of women diagnosed with breast cancer. This increase, which is associated with the advancements in treatment modalities, emphasizes the need to evaluate the health-related quality of life (HRQoL) of women with breast cancer and to compare its patterns before and after breast-conserving surgery (BCS). Objective: This study aims to describe changes in HRQoL according to body image pre- and post-BCS and just before initiation of adjuvant therapy in newly diagnosed patients with breast cancer in Lebanon. Methods: A prospective cohort study targeting Lebanese women newly diagnosed with breast cancer and who have an indication for BCS will be conducted in 2 health care facilities.
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