Abstract
BackgroundThe assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. No HRQOL study, however, has looked at HRQOL in patients with chronic gastritis and peptic ulcers. This paper focuses on comparing HRQOL in patients with chronic gastritis and peptic ulcers and examining the factors that influence the HRQOL of such patients. Results can be used for making decisions in clinical trials as well as aiding individual management and preventive care of these diseases.MethodsThe Chinese version of the SF-36 (CSF-36) was administered twice to 244 patients with chronic gastritis and peptic ulcers. Mean scores across the two disease groups were compared using t-tests, change over time was analyzed with paired samples t-tests, and factors predicting HRQOL were investigated using the univariate general linear model.ResultsThe mean domain scores of patients with chronic gastritis were lower than those for patients with peptic ulcers, with the exception of physical functioning. Both groups had lower HRQOL compared with population norms. Mean domain scores increased after treatment in both groups. HRQOL in patients with these two chronic diseases differed by age, education level, marriage, income, and gender, but their explanatory power was relatively low.ConclusionQuality of life of patients with chronic gastritis was lower than that of patients with peptic ulcers, which was lower than population norms. Quality of life in both patients groups was associated with socio-demographic risk factors.
Highlights
The assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases
The social functioning (SF)-36 has been translated into many foreign languages and is used in more than 40 countries as part of the International Quality of Life Assessment (IQOLA) project [5]
We found that patients with chronic gastritis had lower quality of life compared with
Summary
The assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. Diseases of the digestive system such as gastritis, functional gastrointestinal disorders, and peptic ulcers are common throughout the world [1,2,3]. While these are not generally life-threatening conditions, they can significantly impair patients’ quality of life (QOL). These digestive system diseases are important to public health because they are remarkably common, can hinder a. It was concluded that the Chinese (mainland) version of the SF-36 functioned in the general population quite to the original American population tested [6]
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