Abstract
Objective: To study the health related quality of life of pregnant women with gestational diabetes mellitus and diabetes mellitus during pregnancy. Method: A cross sectional study done using the SF-36 questionnaire on pregnant women with gestational diabetes mellitus and diabetes mellitus during pregnancy (n=294) and compared with a control group (n=306) of pregnant women. Results: A total of 600 participated with 294 patients with diabetes and gestational diabetes and 306 controls. The physical component score was lower in the GDM/DM group (t = 1.969) showed a significant difference (P=0.049, CI = 0.003-2.87) compared to the controls. The mental health score (t =0.041) did not show any significant difference (P=0.968, CI =-1.45-1.52) between the two groups. Sub group analysis of the 8 components showed a significant difference in the physical function component (P=0.032) and the bodily pain component (P=0.041) where the group with gestational diabetes/diabetes group showed a worse health related quality of life. There was no significant difference between physical role (P=0.125) and general health (P=0.212) the other 2 physical health components. All 4 mental health components of the two groups, Vitality (P=0.744), social function (P=0.235), emotional role (P=0.856) and mental health (P=0.464) did not show any significant difference. Conclusion: The physical health of gestational diabetes mellitus/diabetes mellitus pregnant women was lower than that of healthy pregnant women while there is no difference in the mental health between them.
Highlights
A total of 600 participated with 294 patients with diabetes and gestational diabetes and 306 controls
The measurement model of the Social functioning (SF)-3621 hypothesizes that 35 of the 36 items are grouped into eight multi-item scales (physical functioning (PF), role limitations physical (RP), bodily pain (BP), general health perceptions (GH), energy/ vitality (VT), social functioning (SF), role limitations emotional (RE), and mental health (MH) that are aggregated into two summary measures (physical component (PCS), mental component (MCS)
The health-related quality of life (HRQOL) related to physical component score was lower in the GDM/diabetes mellitus (DM) group and showed a significant difference (P=0.049)
Summary
600 pregnant women were recruited for the study. The distribution of age of the study population ranged from 18 to 43 years. Comparison of mean age distribution within the two study populations (GDM/DM group vs control) showed no significant difference (p=0.417). This confirmed that the two study groups showed the same characteristic with regard to age. The HRQOL related to physical component score was lower in the GDM/DM group and showed a significant difference (P=0.049). Sub group analysis of the 8 components showed a significant difference in the physical function component (P=0.032) and the bodily pain component (P=0.041) where the group with GDM/DM showed a worse HRQOL. The mental health components of HRQOL between the two groups Vitality (P=0.744), social function (P=0.235), emotional role (P=0.856) and mental health (P=0.464) did not show any significant difference
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