Abstract
BackgroundColorectal cancer (CRC) is the third most commonly diagnosed cancer in males and the second in females with a progressive increase in prevalence in industrialized countries. The loss of health due to the cancer and/or the consequence of the treatment may result in psychophysical, functional and social impairment; all of these affect health-related quality of life (QoL).DescriptionThe most frequently CRC-specific QoL questionnaires is the FACT-C. QoL is not only important for the well-being of cancer patient but it also influences survival and response to therapy. Many studies investigated various determinants involved in the assessment of QoL in CRC, suggesting that symptoms, surgical procedures and the number of comorbidity significantly affected QoL.ConclusionDespite that CRC patients have a relatively good QoL compared with the general population, a wide range of intervention could be undertaken to improve their QoL. The finding of this review may be useful for cancer clinicians in taking therapy and surveillance-related decisions. However, future research should be directed to large-scale prospective studies using well validated QoL instruments to facilitate comparison of results.
Highlights
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in males and the second in females with a progressive increase in prevalence in industrialized countries
Despite that CRC patients have a relatively good quality of life (QoL) compared with the general population, a wide range of intervention could be undertaken to improve their QoL
Future research should be directed to large-scale prospective studies using well validated QoL instruments to facilitate comparison of results
Summary
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in males and the second in females with a progressive increase in prevalence in industrialized countries. Conclusion: Despite that CRC patients have a relatively good QoL compared with the general population, a wide range of intervention could be undertaken to improve their QoL. * Correspondence: abiondi@unict.it 4Department of General Surgery, Section of General Surgery and Oncology, University Medical School of Catania, Italy Full list of author information is available at the end of the article impact on health-related quality of life (QoL) [7].
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