Abstract

Skin diseases have caused a heavy burden on the infected population worldwide. This study aimed to examine the health-related quality of life (HRQOL) among patients with different skin diseases and identify associated factors. A cross-sectional study with 430 participants was conducted at the Vietnam National Hospital of Dermatology and Venereology (NHD) from September to November 2018. The EuroQol-5 Dimensions-5 Levels (EQ-5D-5L) instrument was employed, which measures the EQ-5D index from five domains including mobility, self-care, usual activity, pain/discomfort, and anxiety/depression. Multivariate Tobit regression was adopted to determine factors that were associated with HRQOL (EQ-5D index). The rate of atopic dermatitis was the highest with 28.8%, following by contact dermatitis (17.0%) and skin fungal infections (13.0%). Regarding HRQOL, anxiety/depression was the most common health problem in patients with skin diseases (71.8%), following by pain/discomfort (63.6%). The mean EQ-5D index score was 0.73 (SD = 0.19). The lowest EQ-5D index scores were obtained for females with skin infections (mean = 0.52) and for males with psoriasis (mean = 0.59). Females had significantly lower scores compared to males (Coef. = −0.06; 95% CI = −0.11 to −0.01). Higher income and living in rural areas were also negatively correlated with the EQ-5D index. This study demonstrated the low HRQOL among patients with skin diseases in Vietnam and emphasized the vulnerability of patients with different socioeconomic statuses to their HRQOL.

Highlights

  • Skin diseases have been causing heavy burden all over the world regardless of age and gender, especially in tropical regions [1]

  • Dermatitis accounts for the highest burden compared to other skin diseases with 0.38% of total disease burdens globally, following by acne vulgaris (0.29%), psoriasis (0.19%), and urticaria (0.19%) [2]

  • We conducted a cross-sectional study at the outpatient clinic in the Vietnam National Hospital of Dermatology and Venereology (NHD) during the period of September–November 2018

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Summary

Introduction

Skin diseases have been causing heavy burden all over the world regardless of age and gender, especially in tropical regions [1]. According to The Global Burden of Disease project, skin diseases were estimated to cause 41.6 million disability-adjusted life years (DALYs)—equivalent to 1.79% of the total burden of diseases [2], ranking the fourth among causes of non-fatal morbidity worldwide [3]. Dermatitis accounts for the highest burden compared to other skin diseases with 0.38% of total disease burdens globally, following by acne vulgaris (0.29%), psoriasis (0.19%), and urticaria (0.19%) [2]. Skin diseases cause a wide range of detrimental effects on all aspects of a patient’s life. They may suffer from physical impairment, psychological distress, and even mortality [5]. Severe skin-related symptoms on the face and body can deteriorate self-esteem and self-confidence of patients, which significantly affect their involvement in social activities [8,9,10]

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