Abstract

Background: The Hereditary Spastic Paraplegias (HSP) comprise of a clinically and genetically heterogeneous group of neurodegenerative disorders characterised by a slowly progressive spastic gait disorder. Clinically, „pure“ and „complicated“ forms are distinguished. The impact of HSP on quality of life is not known so far. Therefore, we assessed the health-related quality of life with the Short-Form 36 (SF-36) quality of life questionnaire in a sample of HSP patients of the GeNeMove network project.

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