Abstract
Objective:to characterize deaths that occurred, and the association between socio-demographic, clinical, laboratory variables and health-related quality of life and the outcome of death in patients on peritoneal dialysis, over a two year period after an initial assessment. Method:observational, prospective population study with 82 patients on peritoneal dialysis. The instruments used for the first stage of data collection were the mini-mental state examination, a sociodemographic, economic, clinical and laboratory questionnaire and the Kidney Disease and Quality of Life-Short Form. After two years, data for characterization and occurrence of death in the period were collected. The relative risk of death outcome was calculated through statistical analysis; the risk of death was estimated by the survival Kaplan-Meier curve, and determined predictors of death by the Cox Proportional Hazards Model. Results:of the 82 original participants, 23 had as an outcome death within two years. The increased risk for the outcome of death was associated with a lower mean score of health-related quality of life in the physical functioning domain. Conclusion:the worst health-related quality of life in the physical functioning domain, could be considered a predictor of death.
Highlights
Mortality among patients on dialysis has decreased over time, due mainly to advances in treatment; when compared to the general population, mortality is still very high in patients on dialysis
The mortality of patients on peritoneal dialysis (PD) in the United States decreased by 15% between 1993 and 2002, and 35% between 2003 and 2012(1)
This study investigated the health-related quality of life (HRQOL) of the 82 PD patients, by mean of the KDQOL-SFTM in 2010; at that time the physical functioning dimension achieved one of the lowest mean scores of the entire instrument, it was the dimension selected to compose the analyses related to death and survival of patients in this study
Summary
Mortality among patients on dialysis has decreased over time, due mainly to advances in treatment; when compared to the general population, mortality is still very high in patients on dialysis. In addition to the interest in increasing the survival time, there is concern about how these patients experience the years aggregated with advances in treatment. Some studies have demonstrated that this dialysis modality generally ensures greater satisfaction with treatment and less impact on the lives of patients, when compared with hemodialysis[2]. Peritoneal dialysis has been used for more than 30 years in Brazil; publications on the epidemiology and clinical experience in this type of treatment, as well as the number of patients who opt for it, are incipient[3,4]
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