Abstract
Health-related quality of life is a broad concept reflecting a patient’s general subjective perception of the impact an illness and treatment given for them. It measures an integral part of patient follow up by providing valuable feedback about the disease as well as associated interventions. The aim of this study was to assess health related quality of life and associated factors among HIV patient on highly active antiretroviral therapy at Assossa general hospital. Institution based cross-sectional study design was conducted among HIV positive patient from February, 8 to March, 21st 2018 at Assossa general hospital. Data was collected using medical outcome study HIV questionnaire, systematic sampling technique was used, entered in to Epi-info software version 7 analyzed using the statistical product and service solution version 20. Bivariate at p-value < 0.2 and Multivariate Logistic regression p-value at <0.05 was used to identify factors associated with health related quality of life. Three hundred participants with 96.5% response rate were involved in the study. About fifty six point seven percent of the study participants mean (±SD) score of overall health related quality of life was 54.85±11.3. Participant that had viral load copies of forty and below were AOR=3.19 (95%CI 1.73, 5.91) associated with good health related quality of life and participant who have no recent opportunistic infection were AOR=2.87 (95%CI 1.49, 5.51) associated with good health related quality of life. Therefore, the health related quality of life was good. Occupational status, living condition viral load copies/ml and opportunistic infection showed association with good health related quality of life and Further research was suggested.
Highlights
Human immunodeficiency virus (HIV) is the virus that attacks white blood cells that are crucial to the normal functioning of the immune system and which protects the body against illness
HIV/Acquired Immunodeficiency Syndrome (AIDS) pandemic remains the most serious of infectious disease challenges to public health but following the emergency of highly active antiretroviral therapy (HAART) changed the disease’s natural course, marking a considerable reduction in mortality, the occurrence of opportunistic infections, the time of hospitalization, and the time interval until progression to AIDS [2]
The study participants who were living with their family and friends AOR=1.49 (95%CI 1.14, 3.34) time more likely to have good health related quality of life than those who were living alone and participants that had viral load copies of forty and below were AOR=3.19 times more likely to have good health related quality of life as compared to their counterpart. participant who has no recent opportunistic infection were AOR=2.87 times more likely to have good health related quality of life as compared to those who had opportunistic infection
Summary
Human immunodeficiency virus (HIV) is the virus that attacks white blood cells that are crucial to the normal functioning of the immune system and which protects the body against illness. Whereas Acquired Immunodeficiency Syndrome (AIDS) which occurs when the immune system is weakened by HIV to the point where a person is susceptible to any number of Opportunistic Infections (OIs) or diseases [1]. As of World Health Organization (WHO), “Quality of life is defined as an individuals’ perception of their position in life in the context of the culture and value systems in which they live in relation to their goals, expectations, standards and concerns”. This indicates individuals satisfaction depends on their physical, mental, social relationships, cognitive and spiritual aspects of their life [4, 5].
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