Abstract
Healing Spinal Cord Injuries
Highlights
Unlike those in the periphery, nerve fibers in the central nervous system do not recover from traumatic injury
In an effort to understand the basic mechanisms of axon regrowth, Ping Yip and colleagues report how a protein called neuronal calcium sensor-1 (NCS1) can help repair central nervous system (CNS) damage in rats
Yip and colleagues have previously shown that axons can regenerate in CNS neurons that overexpress retinoic acid receptor b2, a protein that regulates cell growth, and observed that this regeneration is accompanied by a rise in NCS1 protein
Summary
Unlike those in the periphery, nerve fibers in the central nervous system (brain and spinal cord) do not recover from traumatic injury. In an effort to understand the basic mechanisms of axon regrowth, Ping Yip and colleagues report how a protein called neuronal calcium sensor-1 (NCS1) can help repair central nervous system (CNS) damage in rats. Yip and colleagues have previously shown that axons can regenerate in CNS neurons that overexpress retinoic acid receptor b2, a protein that regulates cell growth, and observed that this regeneration is accompanied by a rise in NCS1 protein.
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