Abstract

<p class="Abstract">In the present study, the ability of mineral trioxide aggregate in the formation of apical plug for healing of large periapical lesion with open apex was assessed and evaluated the clinical outcome. Fifteen participants with periapical lesion at the upper anterior teeth with open apex were treated with mineral trioxide aggregate. The effect on healing of apical size was evaluated at 3, 6, and 12 months by radiological examinations in the form of periapical index criteria, diameter of the lesion size and the presence or absence of apical tissue barrier. The results found that neither pain nor any sinus was detected at 12 months. The mean size of the apical lesion was gradually reduced from 5.1 × 3.8 to 1.5 × 0.9 mm and mean PAI was reduced from 3.3 to 1.7 mm. The differences between mean size of periapical lesion at preoperative and 12 months observation period was also statistically significant (p<0.05). The clinical success shown significant success rate of 93.3% analyzed with Z-test. In conclusion, tooth with open apex can be successfully treated with mineral trioxide aggregate apexification technique followed by root canal obturation.</p>

Highlights

  • Traumatic injuries generally interrupt the pulpal blood supply results in necrosis of the pulp and develop anaerobic conditions favorable for the growth of opportunistic microorganisms. This condition often leads to the development of periapical lesions.[1]

  • The mean size of lesion was reduced from 5.1 × 3.8 to 1.5 × 0.9 mm at 12 months

  • At 12 months, clinical success rate of 93.3% in mineral trioxide aggregate was achieved with Ztest

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Summary

Introduction

Traumatic injuries generally interrupt the pulpal blood supply results in necrosis of the pulp and develop anaerobic conditions favorable for the growth of opportunistic microorganisms This condition often leads to the development of periapical lesions.[1] patient with teeth that were incompletely developed or had open apices further complicate the condition which is difficult to manage. Several materials are used to form an apical barrier These include calcium hydroxide powder, collagen calcium phosphate, osteogenic protein, bone growth factor, oxidized cellulose and mineral trioxide aggregate.[1] Mineral trioxide aggregate was originally developed as the root canal filling material. It can be carried out in a single visit and has many advantages over the traditional calcium hydroxide apexification. The capability of mineral trioxide aggregate in the formation of apical plug or barrier for healing of large periapical lesion with open apex was observed and evaluated the clinical outcome

Materials and Methods
Therapeutic procedure
Results
Discussion
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