Abstract
The incidence and clinical features of headache in 60 children, aged 5 to 18 years, with brain tumors were determined and compared to the pattern of primary headaches in 50 children (migraine without aura (25) and tension-type headaches (25)), in a study at the University of Padua, Italy.
Highlights
The incidence and clinical features of headache in 60 children, aged 5 to 18 years, with brain tumors were determined and compared to the pattern of primary headaches in 50 children (migraine without aura (25) and tension-type headaches (25)), in a study at the University of Padua, Italy
A controlled multicenter trial of lamotrigine (LTG) monotherapy compared to valproate (VPA) for partial seizures in adults found 56% successfully maintained on LTG compared to 20% on VPA
In the group with brain tumors, headache was the first symptom in 27% and the only presenting feature in 10%
Summary
The incidence and clinical features of headache in 60 children, aged 5 to 18 years, with brain tumors were determined and compared to the pattern of primary headaches in 50 children (migraine without aura (25) and tension-type headaches (25)), in a study at the University of Padua, Italy. Clobazam (CLB) has equivalent efficacy to carbamazepine and phenytoin as monotherapy for childhood epilepsy, according to a report from a Canadian Study Group for Childhood Epilepsy (Camfield P et al Epilepsia 1998;39:952-959). The authors conclude that CLB should be considered a first line monotherapy for partial and selected generalized childhood epilepsies.
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