Abstract

Investigators from University of Texas Southwestern Medical Center, Dallas, TX, and other centers in the US and London, UK, studied risk factors for headache and migraine in 872 children, age 5 to 15 years (mean age, 9.1 years), with sickle cell disease (hemoglobinSS or hemoglobinSb-thalassemia) and no history of overt stroke or seizures.

Highlights

  • Investigators from University of Texas Southwestern Medical Center, Dallas, TX, and other centers in the US and London, UK, studied risk factors for headache and migraine in 872 children, age 5 to 15 years (mean age, 9.1 years), with sickle cell disease (hemoglobinSS or hemoglobinSb-thalassemia) and no history of overt stroke or seizures

  • Lower Hgb concentration, and higher pain event rate were associated with recurrent headaches and migraines

  • In a study of children with sickle cell disease (SCD) who presented acutely with headache, headache was the chief complaint in 3.8% of acute care visits, and acute CNS events occurred in 16.9%

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Summary

Introduction

Investigators from University of Texas Southwestern Medical Center, Dallas, TX, and other centers in the US and London, UK, studied risk factors for headache and migraine in 872 children, age 5 to 15 years (mean age, 9.1 years), with sickle cell disease (hemoglobinSS or hemoglobinSb-thalassemia) and no history of overt stroke or seizures. Recurrent headaches were reported in 317 (36.4%) and migraines in 132 (15.1%).

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