Abstract
The study of head regeneration in hydra should lead to insights into the more general mechanisms of pattern formation. From the tissue of hydra, two morphogenetic substances have been isolated, the head activator and the head inhibitor, which seem to have high significance for the regulation of such processes. Studies of the changes of the concentrations of head inhibitor and head activator during hydra head regeneration have shown that free head inhibitor blocks its own release from sources and that of head activator as well. On the basis of this feedback mechanism a system of differential equations was formulated which describes the changes of the free and bound substances during regeneration in a computer simulation.
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