Abstract

The cardinal symptoms of some ophthalmic diseases observed through exceptional retinal blood vessels, such as retinal vein occlusion, diabetic retinopathy, etc. The advanced deep learning models used to obtain morphological and structural information of blood vessels automatically are conducive to the early treatment and initiative prevention of ophthalmic diseases. In our work, we propose a hierarchical dilation convolutional network (HDC-Net) to extract retinal vessels in a pixel-to-pixel manner. It utilizes the hierarchical dilation convolution (HDC) module to capture the fragile retinal blood vessels usually neglected by other methods. An improved residual dual efficient channel attention (RDECA) module can infer more delicate channel information to reinforce the discriminative capability of the model. The structured Dropblock can help our HDC-Net model to solve the network overfitting effectively. From a holistic perspective, the segmentation results obtained by HDC-Net are superior to other deep learning methods on three acknowledged datasets (DRIVE, CHASE-DB1, STARE), the sensitivity, specificity, accuracy, f1-score and AUC score are {0.8252, 0.9829, 0.9692, 0.8239, 0.9871}, {0.8227, 0.9853, 0.9745, 0.8113, 0.9884}, and {0.8369, 0.9866, 0.9751, 0.8385, 0.9913}, respectively. It surpasses most other advanced retinal vessel segmentation models. Qualitative and quantitative analysis demonstrates that HDC-Net can fulfill the task of retinal vessel segmentation efficiently and accurately.

Highlights

  • The study found that the number of patients with retinopathy increases with the advent of an aging population

  • The hierarchical dilation convolutional network (HDC-Net) model was evaluated on the DRIVE, CHASE-DB1, and STARE datasets, respectively

  • We have developed a retinal vessel segmentation framework based on deep learning

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Summary

Introduction

The study found that the number of patients with retinopathy increases with the advent of an aging population. There are many reasons for retinopathy, such as diabetes, nephritis, anemia, influenza, which may cause fundus diseases. The clinical symptoms of retinopathy are mainly manifest in changes in the length, width, curvature, and angle of the retinal blood vessels [1]. Diabetic retinopathy [2] is associate with swelling of the blood vessels, and hypertensive retinopathy [3] is accompanied by increased retinal vessel curvature and narrowing of blood vessels. Retinopathy can be observed in many ways, the most critical characteristic is the variation of retinal blood vessels. To enable sufferers to receive reasonable treatment, ophthalmologists usually diagnose related diseases by observing the morphological features of the abnormal blood vessels. To observe exceptional blood vessels more intuitively, it is most crucial to analyze blood

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