HCV resistance test guided retreatments after protease inhibitors failures can induce maximal efficacy rate in real-life

Valeria Cento ,L Lambiase,V.C Di Maio,Elisa Biliotti ,Stefania Paolucci ,Tina Ruggiero ,Maria Grazia Melis ,Stefano Bonora ,Massimo Siciliano ,Elisabetta Teti ,Massimo Puoti ,Chiara Masetti ,Margherita Macera ,Martina Mihalj ,Barbara Menzaghi ,S Marenco ,M Angélico ,Sergio Babudieri ,Valeria Ghisetti ,Antonio Di Biagio ,Antonino Picciotto ,C Sarrecchia ,C Magni ,Silvia Barbaliscia ,A Bertoli ,Dante Romagnoli ,Gloria Taliani ,Ye A Troshina ,A Pecchioli ,Fausto Baldanti ,Elena Danieli ,Massimo Andreoni ,F.p Antonucci ,Vito Messina ,Adriano Pellicelli ,Ilaria Lenci ,Ernesto Claar ,Nicola Coppola ,Laura Ambra Nicolini ,Alessia Ciancio ,Giuliano Rizzardini ,C Pasquazzi ,M Aragri ,Loredana Sarmati ,Stefano Novati ,Valeria Micheli ,Carlo Federico Perno ,Francesca Ceccherini‐Silberstein

doi:10.1016/j.dld.2017.01.107

HCV resistance test guided retreatments after protease inhibitors failures can induce maximal efficacy rate in real-life

Valeria Cento , L Lambiase + Show 46 more

https://doi.org/10.1016/j.dld.2017.01.107

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Journal: Digestive and Liver Disease

Publication Date: Feb 1, 2017

Affiliation: University of Rome Tor Vergata, Azienda Ospedaliera Sant'Andrea, Policlinico Umberto I, Policlinico San Matteo Fondazione, Ospedale Amedeo di Savoia, University of Sassari, Università Cattolica del Sacro Cuore, Ospedale Niguarda Ca' Granda, University of Naples Federico II, University of Campania "Luigi Vanvitelli", Ospedale di Circolo di Busto Arsizio, Ospedale Policlinico San Martino, University of Genoa, ASST Fatebenefratelli Sacco, University of Turin, San Camillo IRCCS di Venezia, Villa Pineta Hospital

#IFN-free Regimens #Genotypic-resistance-testing + Show 8 more

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Abstract

Background and aims: We analyzed the efficacy of retreatment after protease inhibitors (PI) plus pegylated-interferon (pegIFN) and ribavirin (RBV)-failure with various IFN-free regimens, and the role of genotypic-resistance-testing (GRT) in real-life settings.

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