Hazards and Detection Techniques of Veterinary Drug Residues in Animal-Origin Food

Zhongyu Chen,T Zhu,A Sharifi,M Anpo

doi:10.1051/e3sconf/202127104033

Abstract

Veterinary drugs originally used to diagnose, prevent, control and treat animal diseases. However, now some of them can also be mixed into livestock feed as growth promoters. Although most countries have specified animal-derived veterinary drug residue standards, such as the maximum residue limit, withdrawal period and prohibition of some veterinary drugs as growth promoters, there are still some animal-derived products with illegal amount of drug residues. Consequently, long-term intake of products with excessive residues will result in irreversible impacts on human health, livestock industries and natural environment. To minimize these risks, the techniques of drug residues detection plays an important role in guarding food safety of animal products. Moreover, Veterinary drug residue detection technology, according to the author's opinion, can be divided into instrumental method, immunoassay method, biomolecular technology and bio-sensor technology. The purpose of this article is to collect and summarize the existing journal literature current about status, hazards and detection techniques of animal-origin veterinary drug residues so that ordinary readers can briefly understand the research status of the residue detection techniques, farmers can understand the importance of regulating and suitable handling of veterinary drugs, and relevant researchers may know about the emphasized difficulties that need to be overcome in drug residue detection techniques.

Highlights

Food safety has usually been the focus of the public
In order to protect public health, the EU has set maximum residue limits (MRLs) based on scientific assessment of the safety of drugs in animal foods, including all kinds of such chemicals in all production varieties[11].and addition strategy is withholding period, which refers to the time from the most recent use of veterinary drugs to the collection and consumption of eggs/milk and meat of such animals
The results showed that 90.9% of milk samples were positive for penicillin residues (0.27-0.77UG/KG), but the detection results of tetracycline and penicillin residues in yogurt were below the detection limit of ELISA [43]

Summary

Introduction

Food safety has usually been the focus of the public. With the development of veterinary pharmacy, the emergency and improvement of veterinary drugs bring about the positive impact on the livestock and poultry industries probably, such as the control and prevention of disease. Apart from the United States and New Zealand, it witnessed a descending tendency in usage antibiotics among most countries [8].Among them, tetracycline, for example, is still the most commonly used veterinary drug [9][8] because of its treatment of respiratory diseases (oxytetracycline, aureomycin, doxycycline, etc.) They are still widely used in farm animals [10]. From the time of handling food animals to the time of slaughtering animals as food, the withdrawal period must be followed because there may be unmetabolized veterinary drug residue exceeds the allowable limit before the end of the withdrawal period Such animal productions may be considered harmful to the human body or significantly increase bacterial resistance. The sales of veterinary drugs in several major antibiotic consumers such as China, India, and Canada are still unavailable [8]

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