Hazardous Medications in Children with Egg, Red Meat, Gelatin, Fish, and Cow's Milk Allergy.

Sule Caglayan-Sozmen,Carlo Caffarelli,Carla Mastrorilli,Angelica Santoro,Giampaolo Ricci,Francesca Cipriani

doi:10.3390/medicina55080501

Abstract

Childhood food allergies are a growing public health problem. Once the offending food allergens have been identified, a strict elimination diet is necessary in treatment or prevention of most of the allergic reactions. Accidental food ingestion can lead to severe anaphylaxis. Food- derived substances can be used in medications at various stages of the manufacturing process. In this review, the possible roles of medications which may contain egg, red meat, gelatin, and fish allergens on allergic reactions in children with food allergy were evaluated.

Highlights

Food allergies among children have been increasing in prevalence in the last two to three decades [1]
The aim of this review is to provide existing data about egg, red meat, gelatin, and fish allergens in medications
Articles were considered if they described systematic reviews, or original meta-analysis, randomized-controlled trials, observational studies, and case reports on food allergens in medications in children up to 18 years of age

Summary

Introduction

Food allergies among children have been increasing in prevalence in the last two to three decades [1]. The cornerstone of treatment for food allergy is the strict avoidance of food allergens and the use of dietary substitutions. Food allergy reactions can range from mild skin rashes to severe, potentially lethal, anaphylaxis [2]. In order to prevent such reactions, individualized advice and education on how to manage an elimination diet should be provided for parents [3]. Hidden food allergens in medications can lead to unpredictable allergic reactions. Food-derived substances are used to protect, support, or enhance stability or for bioavailability or for patient acceptability during the manufacturing process of medications [4]. The aim of this review is to provide existing data about egg, red meat, gelatin, and fish allergens in medications

Objectives

Methods

Findings

Conclusion