Abstract

La sepsis es la primera causa de muerte por infección en el mundo y el pronóstico es tiempo dependiente de un tratamiento eficaz. Existen descritos numerosos factores pronósticos en la bibliografía sin embargo hay pocos estudios que los comparen entre ellos para valorar si hay alguno con mayor peso frente a otros. El presente artículo, con una muestra de 82 pacientes, analiza diferentes factores pronósticos en las primeras 24 horas de ingreso como indicadores de supervivencia a los 28 días. Estos son: cifras de lactato, su tasa de eliminación, la saturación venosa central y la diferencia entre la saturación de oxígeno arterio-venosa central. Los resultados muestras que las cifras de lactato a las 24 horas son los que presentan una sensibilidad-especificadad mayores (punto de corte de 2,15 mmol/dl), seguido por la cifra de lactato a las 12 y a las 6 horas. ABSTRACT Are there prognostic factors for mortality in the septic patient in the ICU? The value of the serum lactate elimination rate Sepsis is the first cause of death due to infection in the world and the prognosis is time dependent on effective treatment. There are numerous prognostic factors described in the literature, however there are just a few studies comparing them among them to assess if there is one with greater weight compared to others. The present article, with a sample of 82 patients, analyzes different prognostic factors in the first 24 hours of admission as survival indicators at 28 days. These are: lactate numbers, their elimination rate, central venous saturation and the difference between central arteriovenous oxygen saturation. The results show that the lactate levels at 24 hours are the ones with higher sensitivity-specificity (cut-off point of 2.15 mmol / dl), followed by the lactate levels at 12 and at 6 hours.

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