Abstract

AbstractA procedure is described for the conversion of acetates of Δ6a, 1 0 a‐THC's (2 and 4a) to their corresponding 7‐oxo‐derivatives (3a, b, d and 4b) by oxidation with ceric ammonium nitrate. The differences between the nmr spectra of these 7‐oxo‐derivatives and the 10‐oxo‐THC (1) are discussed. The 7‐oxo‐derivatives show THC‐like activity in mice albeit less than their corresponding THC's.

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