Abstract
Harmonic motion imaging (HMI) is a radiation force-based elasticity imaging technique that estimates tissue harmonic displacements induced by an oscillatory ultrasonic radiation force to assess tissue stiffness. The objective of this study was to evaluate the feasibility of applying HMI on pancreatic tumor detection and high-intensity focused ultrasound (HIFU) treatment monitoring.
Highlights
Background/introduction Harmonic motion imaging (HMI) is a radiation forcebased elasticity imaging technique that estimates tissue harmonic displacements induced by an oscillatory ultrasonic radiation force to assess tissue stiffness
The HMI system consisted of a focused ultrasound transducer (FUS), which generated oscillatory radiation force that induced harmonic tissue motion at 50 Hz at the focus, and a diagnostic ultrasound transducer, which detected the axial tissue displacement within the targeted region using 1D cross-correlation of acquired radiofrequency signals
HMI monitoring of the high-intensity focused ultrasound (HIFU) ablation depicted consistent pancreatic stiffening with a mean HMI displacement reduction rate of 25% after 2 min ablation, and the formation of thermal lesions was confirmed by the histological analysis
Summary
Harmonic motion imaging for pancreatic tumor detection and high-intensity focused ultrasound ablation monitoring Background/introduction Harmonic motion imaging (HMI) is a radiation forcebased elasticity imaging technique that estimates tissue harmonic displacements induced by an oscillatory ultrasonic radiation force to assess tissue stiffness. The objective of this study was to evaluate the feasibility of applying HMI on pancreatic tumor detection and high-intensity focused ultrasound (HIFU) treatment monitoring.
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