Handheld ultrasound-guided 20 mm basket Intact breast lesion excision system biopsy for excision of benign breast lesions

Alice Leaver,Alan Redman,Simon Lowes,Peter Newton,Dianne Hemming,Alice Townend,Jackie Westgarth

doi:10.1186/bcr3789

Abstract

In selected patients, our Unit has recently moved from handheld ultrasound-guided vacuum-assisted core biopsy (VACB) piecemeal acquisition of tissue to the handheld Intact Breast Lesion Excision System (Intact). Intact removes a single piece of tissue, potentially allowing radiologists to excise the entire lesion as well as allowing pathologists to visualise lesion architecture more easily and to calculate margins. We evaluated our early experience of excising benign or likely benign breast lesions using the 20 mm Intact.

Highlights

The aim was to compare the accuracy of standard supplementary views and GE digital breast tomosynthesis (DBT) for assessment of soft tissue mammographic abnormalities
The measured parameter is the volume averaged speed of sound (VASS) [1,2]. It improves on mammography by measuring density at each voxel and holds promise as a cheap, patient-acceptable, non-ionising radiation method to evaluate density
This study was to evaluate the technique of Ultrasound tomography (UST) and compare VASS with percentage water density from non-contrast magnetic resonance imaging (MRI)

Summary

Introduction

The aim was to compare the accuracy of standard supplementary views and GE digital breast tomosynthesis (DBT) for assessment of soft tissue mammographic abnormalities. Methods: Prospective audit of data collated at the time of the microbubbles procedure together with multidisciplinary meeting records identified relevant screening and symptomatic patients with primary breast cancer treatment including axillary node surgery between 1 July 2014 and 1 July 2015. Breast MRI can be performed in the preoperative workup of patients with biopsy-proven breast cancer to size lesions, if there is discrepancy regarding the extent of disease from clinical, mammography or ultrasound assessment, and to identify multicentric or multifocal disease. Conclusion: MRI is more sensitive than the other three imaging modalities combined in accurately identifying multifocal breast cancer; DBT is still a useful adjunct in the evaluation of multifocal disease. Retrospective review of 399 patients who underwent biopsy for breast microcalcification during screening assessment from April 2012 to March 2013 was used to evaluate the performance and cost-effectiveness of both methods. Radiologist time may be better directed towards meeting the symptomatic breast 2-week wait standard

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