Abstract
Hand hygiene is of utmost importance as it may be contaminated easily from direct contact with airborne microorganism droplets from coughs and sneezes. Particularly in situations like pandemic outbreak, it is crucial to interrupt the transmission chain of the virus by the practice of proper hand sanitization. It can be achieved with contact isolation and strict infection control tool like maintaining good hand hygiene in hospital settings and in public. The success of the hand sanitization solely depends on the use of effective hand disinfecting agents formulated in various types and forms such as antimicrobial soaps, water-based or alcohol-based hand sanitizer, with the latter being widely used in hospital settings. To date, most of the effective hand sanitizer products are alcohol-based formulations containing 62%–95% of alcohol as it can denature the proteins of microbes and the ability to inactivate viruses. This systematic review correlated with the data available in Pubmed, and it will investigate the range of available hand sanitizers and their effectiveness as well as the formulation aspects, adverse effects, and recommendations to enhance the formulation efficiency and safety. Further, this article highlights the efficacy of alcohol-based hand sanitizer against the coronavirus.
Highlights
The emergence of the COVID-19 (Coronavirus Disease-2019) pandemic has risen to be a significant global public health concern and led to extensive use of hand disinfectants given its contagious nature
Hand disinfectants are commercially available in various types andforms forms such such as anti-microbial soaps, water-based or alcohol-based handhand sanitizers, most most oftenoften used in hospital settings
Of many we reports, we selected articlesonbased on the hand disinfectant agents andpotential their potential many selected articles based the hand disinfectant agents and their outcome outcome suitable for the present viral pandemic
Summary
The emergence of the COVID-19 (Coronavirus Disease-2019) pandemic has risen to be a significant global public health concern and led to extensive use of hand disinfectants given its contagious nature. Hand disinfectants are commercially available in various types andforms forms such such as anti-microbial soaps, water-based or alcohol-based handhand sanitizers, most most oftenoften used in hospital settings. As anti-microbial soaps, water-based or alcohol-based sanitizers, used in hospital settings.types. There are a fewchallenges challengesand andconcerns concerns with with regard of of fire hazards andand skin toxicity content[21] This systemic review aims to investigate the range skin toxicitydue dueto tohigh high alcohol alcohol content systemic review aims to investigate the range of of available availablehand handsanitizers sanitizersand andtheir theireffectiveness effectiveness against the human coronavirus as well against the human coronavirus as well as as thethe formulation recommendationstotoimprove improvethe theformulation formulation current formulationaspects, aspects,adverse adverse effects, effects, and and recommendations of of current hand sanitizers
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