Abstract
A halogen-bond-promoted atom transfer radical addition of alkynes with perfluoroalkyl iodides under visible light irradiation has been reported. Fluoroalkyl radicals can be generated by a visible-light-induced single electron transfer (SET) process with fluorinated iodides as halogen bond donors and organic bases as halogen bond acceptors. Subsequently fluoroalkyl radicals add to terminal alkynes to afford the corresponding iodoperfluoroalkylated products with high yields and broad substrate scope at room temperature. The resulting perfluoroalkylated alkenyl iodides can be further functionalized by cross-coupling reactions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Photochemistry and Photobiology A: Chemistry
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
