Abstract
Abstract: The Friedel-Crafts alkylation of indole with ketones and aldehydes had been developed for the preparation of 3,3’-diindolylmethanes using iodine or NCS as catalysts. Two mild and efficient catalysis systems were provided for acti-vation of carbonyl compounds and indoles. The reaction proceeded smoothly in ethanol to produce the corresponding prod-ucts with good to excellent yields. Furtherly, the mechanism was speculated.
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