Halo Medium-Sized Congenital Melanocytic Nevi and Vitiligo Progression in Three Children

Jesus Borbujo Diego Martinezsanchez

doi:10.4172/2376-0427.1000149

Abstract

Reports of halo nevus in medium-sized CMN are limited in the literature and its association with vitiligo is not very common. We present three healthy children with medium-sized CMN. There was no family history of vitiligo, other autoimmune disorders or melanoma. After years of follow up, the patients developed an achromic regular halo around the congenital nevus and one of them showed others halo nevi. Following these changes, achromic macules appeared and vitiligo was diagnosed. At follow-up, we observed reduction in size of the CMN and no thought-provoking malignant changes. Conclusion: We support that in halo medium sized CMN, like in other congenital nevi with unusual features, continuous observation should be recommended. Furthermore, parents should be informed about the long period of time required for complete resolution and the low possibility of malignant change in the nevus. Pediatricians should be familiar with this no life-threatening association.

Highlights

Reports of halo nevus in medium-sized Congenital Melanocytic Nevi (CMN) are limited in the literature and their association with vitiligo is not very common [1,2,3]
It is remarkable that most of the reported cases developed vitiligo shortly after the achromic halo expanded around the CMN [1,2,3]
Seven cases were found with vitiligo after halo medium-sized CMN with no sex or age of onset predominance (Table 1)

Summary

Introduction

Reports of halo nevus in medium-sized Congenital Melanocytic Nevi (CMN) are limited in the literature and their association with vitiligo is not very common [1,2,3]. A one year-old girl was referred to our dermatology department for assessment of an asymptomatic congenital pigmented lesion on the right posterior flank. Dermatologic examination revealed a 30×10 mm homogeneous dark brown plaque with a verrucous surface, which was diagnosed as medium-sized CMN. A two year-old girl was under follow-up due to an asymptomatic congenital pigmented lesion on the left leg. She had no relevant past medical and family history. An achromic halo appeared around the CMN and around other pigmented lesions, some of the halos increased in size with disappearance of several nevi and achromic macules randomly distributed were noted. Reduction in size of pigmented lesions with no progression of vitiligo was observed on follow-up. Reduction in size of the CMN and a slow progression of vitiligo were observed (Figure 2)

Discussion

Right knee