Abstract

Hairy cell leukemia (HCL) belongs to a heterogeneous group of B-cell malignancies, which can occasionally be detected in asymptomatic patients. Herein, we report a case of HCL discovered due to the management of the hemolytic episode of cold-antibody autoimmune hemolytic anemia (cAIHA)  developed during the course of a mild form of coronavirus disease 2019 (COVID-19).  Neither the AIHA nor the underlying HCL did affect the course of COVID-19, but the indolent course of HCL showed to have been changed into a clinically overt disease.

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