Abstract
Androgenic alopecia is characterized by progressive loss of hair from the scalp. This research aimed to determine the hair and blood zinc levels in men with androgenic alopecia. The research was conducted in the Departement of Dermatovenereology of Dr. Wahidin Sudirohusodo Hospital, Makassar and the Center for Health Laboratory, Makassar, using the observational research method. The samples comprised 21 males with androgenic alopecia and 11 control samples without androgenic alopecia. The hair and blood of the samples were analyzed using the atomic absorption spectrophotometer receipts. The results showed that there was significant difference (p <0.05) between the levels of androgenic alopecia hair zinc and control. On blood zinc levels found no significant differences between androgenic alopecia and control. Hair zinc levels had a significant relationship with the degree of Hamilton, where the lower the levels of zinc in the hair androgenic alopecia, the greater the degree of Hamilton. However, things are different, between blood zinc levels in hair zinc levels and degrees of Hamilton that there is no significant difference. In this study also found between age and degree of Hamilton, where the increasing age, the greater the degree of Hamilton.
Highlights
Androgenic alopecia or male pattern hair loss is a common progressive hair loss that occurs due to the influence of genetic predisposition and androgens on hair follicles
The pattern of hair loss in women are different from men, but female pattern alopecia is called androgenic alopecia because the characteristics of hair loss similar in both gender, it characterized by shortening the anagen phase, elongation the telogen phase, and downsizing the hair follicles that lead to hair shaft grows thinner in each cycle
We found no significant differences between androgenic alopecia and control
Summary
Androgenic alopecia or male pattern hair loss is a common progressive hair loss that occurs due to the influence of genetic predisposition and androgens on hair follicles. The pattern of hair loss is more diffuse and it starts from the top of the head. The incidence rate in males is higher than in women, it is because men have higher level of 5α-reductase. Hair follicles that undergo miniaturization is a characteristic of androgenic alopecia. The incidence influenced by race, where white men have higher incidence rate than the Asian, American Indian and African male. It was found an increasing incidence of benign prostatic hypertrophy (BPH) in men with androgenic alopecia. It was found an increasing incidence of benign prostatic hypertrophy (BPH) in men with androgenic alopecia. [2, 3]
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