Abstract
The HAIR-AN syndrome is a rare multisystem disorder in women, that consists of hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans (AN). The IR is likely due to a primary defect of the insulin receptor. We report the case of a 25-year-old Caucasian woman with HAIR-AN syndrome, impaired glucose tolerance (IGT), mild hyperlipemia, and hypertension, associated with sclerodermatous skin changes on the extremities and trunk. Though scleroderma may coexist with other autoimmune diseases, its presentation with HAIR-AN syndrome has not yet been described.
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