Abstract
Familial occurrence, comprising 20 individual cases of haemolytic anaemia, are on record among dogs of the Basenji breed in Denmark. Previous evidence suggests that the anaemia is caused by erythrocytic pyruvate kinase deficiency. The present report encompasses a genetic analysis based on pedigree information combined with segregation results. The latter are obtained by truncate selection through affected individuals. The results give strong support for simple, autosomal recessive inheritance. In the pedigree 33 individuals are heterozygous according to genetic criteria. The recessive gene has been traced through 15 generations which include individuals of importance for the breed in various countries.
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