Abstract

The menace of malaria has constituted a health challenge in Nigeria. Internally Displaced Persons’ Camps are available temporary accommodation provided for victims of war in war torn zones around the world. A study was undertaken to investigate relationship between Serum Amyloid A (SAA), haematological profiles and malaria infection among internally displaced person in three (3) different camps (GGC: Government Girls’ College Camp, GSS: Girls’ Secondary School Camp, CAN-: Christian Association of Nigeria) within Maiduguri, Borno state capital between March and September, 2017. A total of 400 sample subjects were recruited for the study, malaria parasite test was done using the Giemsa thick and thin peripheral blood film, SAA was analysed using the Enzyme linked immune-sobent assay (ELISA) kit while Haematological parameters were analyse using the automatic full blood count analyser. The result of the study shows a positive correlation between malaria infection and these parameters. A mean SAA of 32.76mg/l, PCV of 28.2%, haemoglobin of 8.88g/dl, platelets of 116.54×103 /µl, leucocyte of 6.02×103 /mm3 and neutrophils of 3.34×103 /mm3 was recorded in the positive subjects compared to the 14.11mg/l, 41%, 14.81g/dl, 261.46×103/µl, 8.23×103 /mm3 , 4.11×103 /mm3 reported in the negative patients group, this results shows that there are abnormal haematological alterations in malaria subjects compared to the negative control group, hence SAA and haematological parameters can be used as markers of plasmodium infection.

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