Abstract

Background Malaria is known to cause severe health consequences due to its marked effects and alteration on the haematological parameters of infected individuals. This study evaluated the haematological profile of adult individuals infected with the malaria parasite. Methods A retrospective study was conducted using archived data of malaria positive cases from January 2017 to March 15, 2019. Data retrieved included subjects' demographics, malaria parasite count, malaria parasite species, and full blood count parameters. A total of 236 malaria positive subjects were included in the study. Results The study showed that more females were infected with the malaria parasite than males (69.07% and 30.93%, respectively). A total of 87.3% of the study population were infected with Plasmodium falciparum as compared to 12.7% infected with Plasmodium malariae. The commonest haematological abnormalities that were seen in this study were lymphopenia (56.78%), anaemia (55.51%), thrombocytopenia (47.46%), eosinopenia (45.76%), neutropenia (29.24%), monocytosis (21.19%), and leucocytosis (17.37%) in the infected subjects. The mean platelet count of P. falciparum-infected subjects was decreased as compared to the mean platelet count of P. malariae-infected subjects. There was a significant (P value <0.05) decrease in the number of platelet count with every unit increase in parasite density. Conclusion Study participants infected with malaria demonstrated vital changes in haematological parameters with anaemia, thrombocytopenia, lymphopenia, monocytosis, and eosinopenia being the most important predictors of malaria infection especially with P. falciparum species.P. falciparum-infected subjects was decreased as compared to the mean platelet count of

Highlights

  • Malaria infection is a major public health problem in tropical areas

  • Malaria infection in humans is associated with a reduction in the haemoglobin level frequently leading to anaemia, of which the most severe cases are seen in Plasmodium falciparum [4]

  • Malaria infection affects the haematopoietic physiology at any level and influences alterations in the haematological parameters resulting in numerous clinical presentations including anaemia [6]. ese changes involve the major cell types such as red blood cells, leucocytes, and thrombocytes [7]. is study evaluated the haematological profile of adult individuals infected with the malaria parasite

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Summary

Background

Malaria is known to cause severe health consequences due to its marked effects and alteration on the haematological parameters of infected individuals. is study evaluated the haematological profile of adult individuals infected with the malaria parasite. Is study evaluated the haematological profile of adult individuals infected with the malaria parasite. Data retrieved included subjects’ demographics, malaria parasite count, malaria parasite species, and full blood count parameters. A total of 87.3% of the study population were infected with Plasmodium falciparum as compared to 12.7% infected with Plasmodium malariae. E commonest haematological abnormalities that were seen in this study were lymphopenia (56.78%), anaemia (55.51%), thrombocytopenia (47.46%), eosinopenia (45.76%), neutropenia (29.24%), monocytosis (21.19%), and leucocytosis (17.37%) in the infected subjects. E mean platelet count of P. falciparum-infected subjects was decreased as compared to the mean platelet count of P. malariae-infected subjects. Study participants infected with malaria demonstrated vital changes in haematological parameters with anaemia, thrombocytopenia, lymphopenia, monocytosis, and eosinopenia being the most important predictors of malaria infection especially with P. falciparum species

Introduction
Materials and Methods
Data Analysis
Results
Discussion
Conclusion
Limitations and Recommendations

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