Abstract

Two groups of sheep, experimentally infected with different doses of Corynebacterium pseudotuberculosis, were investigated; animals receiving high doses developed a septicaemia and died within 4 days of infection, while those inoculated with moderate doses survived, and were killed 4 weeks after infection with typical lesions of caseous lymphadenitis. A severe haemolytic anaemia, described as transitory macrocytic hypochromic, occurred in animals of the former group, while a less severe normocytic hypochromic anaemia was observed in the latter. Marked changes in plasma proteins and the haematological picture were found in animals of both groups, and these are discussed in relation to post mortem and histopathological findings.

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