Abstract
Haematological and biochemical changes after exposure to Maerua crassifolia ethanol leaf extract in rats
Highlights
Maerua crassifolia Forssk (Capparaceae) is widely used in ethnomedicine for the treatment of different diseases
Acute oral toxicity The ethanol leaf extract produced no adverse effect in rats at the dose levels tested
The food and water intakes were properly accepted by the experimental rats exposed to M. crassifolia leaf extract which suggest that the extract may not have caused any alteration in diets metabolism in these animals
Summary
Maerua crassifolia Forssk (Capparaceae) is widely used in ethnomedicine for the treatment of different diseases. The leaves are used for the treatment of some diseases including analgesic, anti-inflammatory, antipyretic, antibacterial and antioxidant, antimalarial, Phytochemical and antidiarrhoea (Akuodor et al, 2016; Chilaka et al, 2015; Akuodor et al, 2014a; Akuodor et al, 2014d). The presence of different biologically active constituents like alkaloids, terpenoids, tannins, flavonoids, saponins and cardiac glycosides have been revealed in the phytochemical analysis of the leaves (Akuodor et al, 2014 d). Due to wide application and the prolonged intake of M. crassifolia leaf, the present study was designed to study the acute and subacute toxicity profile of ethanol leaf extract of M. crassifolia in experimental rats
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